Ferrostatin-1 (Fer-1): Advancing Translational Research T...
2025-10-18
Ferroptosis, a unique iron-dependent form of regulated cell death, is rapidly gaining prominence in disease modeling and drug discovery. This thought-leadership article provides translational researchers with mechanistic insights, strategic experimental guidance, and a future-facing outlook on the field. By integrating recent mechanistic findings, competitive landscape analysis, and clinical implications, we illustrate how Ferrostatin-1 (Fer-1) stands as an indispensable, selective ferroptosis inhibitor for next-generation research. This perspective uniquely bridges molecular understanding with practical utility, moving beyond standard product guides.